The Distribution and Dimerization of Di-n-butyl Phosphate (DBP) in Different Solvents.
نویسندگان
چکیده
منابع مشابه
Teratogenicity of di(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) in mice.
Di(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) were mixed with diet at graded levels of 0.05, 0.1, 0.2. 0.4 and 1.0 wt-% and given to pregnant ICR mice throughout gestation. Maternal weight gain was suppressed and fetal resorption increased at 0.2, 0.4 and 1.0% levels of DEHP and 1.0% level of DBP. All the implanted ova died early in rats fed 0.4 and 1.0% levels of DEHP. Exter...
متن کاملThyroid Disruption by Di-n-Butyl Phthalate (DBP) and Mono-n-Butyl Phthalate (MBP) in Xenopus laevis
BACKGROUND Di-n-butyl phthalate (DBP), a chemical widely used in many consumer products, is estrogenic and capable of producing seriously reproductive and developmental effects in laboratory animals. However, recent in vitro studies have shown that DBP and mono-n-butyl phthalate (MBP), the major metabolite of DBP, possessed thyroid hormone receptor (TR) antagonist activity. It is therefore impo...
متن کاملGenotoxicity of sub-lethal di-n-butyl phthalate (DBP) in Nile tilapia (Oreochromis niloticus).
This study aimed to assess genotoxicity in Nile tilapia (Oreochromis niloticus) erythrocytes after exposure to a sub-lethal concentration of 10 mg L(-1) di-n-butyl phthalate (DBP) for 24 and 96 h. The results showed that mean MN frequencies in both DBP and ethyl methane-sulfonate (EMS, positive control for MN bioassay) groups were significantly different (p<0.01) with respect to control and sol...
متن کاملMaternal exposure to di-n-butyl phthalate (DBP) induces renal fibrosis in adult rat offspring
This study was to determine the impact of maternal exposure to di-n-butyl phthalate (DBP) on renal development and fibrosis in adult offspring. Pregnant rats received DBP at a dose of 850 mg/kg BW/day by oral perfusion during gestational days 14-18. In DBP exposed newborn offspring, gross observation and histopathological examination revealed the dysplasia of kidney. The expression of genes rel...
متن کاملProposition 65 Maximum Allowable Dose Level (MADL) for Reproductive Toxicity for Di(n-butyl)phthalate (DBP)
The maximum allowable dose level (MADL) for di(n-butyl)phthalate (DBP) is 8.7 micrograms/day (μg/day). This value is based on the reproductive effects of DBP as observed in the study in rats by Lee et al. (2004). In that study, dietary maternal exposure during pregnancy and the lactational period adversely affected development of the reproductive system of male and female rat offspring. Since t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1960
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.14-1091